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4 wrz 2017 · Gross primary production (GPP)—the uptake of carbon dioxide (CO2) by leaves, and its conversion to sugars by photosynthesis—is the basis for life on land.
Gluconeogenesis is a complex metabolic process that involves multiple enzymatic steps regulated by myriad factors, including substrate concentrations, the redox state, activation and inhibition of specific enzyme steps, and hormonal modulation.
16 paź 2020 · This review focuses on the current understanding of carbon flux in gluconeogenesis, including substrate contribution of various gluconeogenic precursors to glucose production. Alterations of gluconeogenic metabolites and fluxes in T2DM are discussed.
7 lip 2022 · 13 CO 2-labeled TCA intermediates (e.g., oxaloacetate or malate) can be used for glucose production (gluconeogenesis) and, hence, produce M + 1 glycolysis intermediates, which then contribute to ribose M + 1 in adenosine through labeling ribose 5-phosphate.
3 maj 2018 · One effective tracer is glucose labeled selectively at carbons 1 and 2 ([1,2-13 C]glucose). Catabolism of this tracer via the oxidative PPP, but not glycolysis, can produce M+1 labeled glycolytic metabolites (Figure 6D). Because the natural isotope M+1 signal is substantial, proper correction for natural isotope abundance is critical.
17 sty 2018 · Atmospheric effects must be taken into account when interpreting terrestrial stable carbon isotopes, with important implications for past environments and climates, and understanding plant ...
21 lut 2018 · Starting from the experimentally measured isotopic distribution in glucose carbon atoms, it yields slightly negative respiratory fractionations (i.e. 13 C-enriched CO 2 compared to glucose), ranging from 0 to −0.5‰, while the values of sucrose fructosyl extend that range to up to −2‰.