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  1. 31 gru 2019 · Interpretation: Thiamine supplementation does not affect glycaemic outcomes, however reduces triglycerides while increasing HDL. Multicentre well-designed RCT with higher doses of thiamine and a follow-up period of 1–2 years will provide better evidence. PROSPERO registration number CRD42020170520. Data availability statement.

  2. 22 lut 2023 · The present systematic review and meta-analysis showed lower systemic concentrations of thiamine, TMP, and total thiamine in individuals with diabetes compared to those without diabetes, while TDP and erythrocyte transketolase activity tended to be lower in the diabetes group without reaching statistical significance.

  3. 23 lis 2022 · A healthcare provider may recommend supplementing with thiamine or other B vitamins if there is a deficiency or if there are symptoms of neuropathy. But taking supplements is not a substitute for any diabetes medications that are needed.

  4. 1 wrz 2024 · Diabetes: Studies suggest people with diabetes may have lower thiamine levels in the body. For people with diabetes who start to develop kidney damage ( nephropathy ), thiamine supplementation might be recommended.

  5. Background: Nutrient supplements are widely used for type 2 diabetes (T2D), yet evidence-based guidance for clinicians is lacking. Methods: We searched the four electronic databases from November 2015–December 2021. The most recent, most ...

  6. 5 cze 2021 · A few pilot studies in humans reported beneficial effects of thiamine administration on diabetic nephropathy, but, despite all promising proofs-of-concept, the possible role of thiamine in counteracting development or progression of retinopathy has not been addressed until now.

  7. High-dose thiamine supplementation may prevent or slow the progression of hyperglycemia toward diabetes mellitus in individuals with impaired glucose regulation.