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15 maj 2012 · Thiamine acts as a coenzyme for transketolase (T k) and for the pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase complexes, enzymes which play a fundamental role for intracellular glucose metabolism by increasing Krebs cycle activity. Therefore, we will review the role of thiamine in the diabetic subjects.
- Thiamine and diabetes: back to the future? - PubMed
Substances. Thiamine. The first reports of a link between...
- Thiamine and diabetes: back to the future? - PubMed
5 cze 2021 · The first reports of a link between thiamine and diabetes date back to the 1940s. Some years later, a role for thiamine deficiency in diabetic neuropathy became evident, and some pilot studies evaluated the putative effects of thiamine supplementation.
8 maj 2020 · Diabetes has been found to be associated with low levels of thiamine stores in the body, as thiamine directly affects carbohydrate metabolism. Amplified renal clearance of thiamine has been found in both type I and type II diabetic patients.
31 gru 2019 · Interpretation: Thiamine supplementation does not affect glycaemic outcomes, however reduces triglycerides while increasing HDL. Multicentre well-designed RCT with higher doses of thiamine and a follow-up period of 1–2 years will provide better evidence. PROSPERO registration number CRD42020170520.
Substances. Thiamine. The first reports of a link between thiamine and diabetes date back to the 1940s. Some years later, a role for thiamine deficiency in diabetic neuropathy became evident, and some pilot studies evaluated the putative effects of thiamine supplementation.
1 wrz 2024 · Diabetes: Studies suggest people with diabetes may have lower thiamine levels in the body. For people with diabetes who start to develop kidney damage (nephropathy), thiamine supplementation might be recommended. Thiamine may also help prevent the cardiovascular complications associated with diabetes.
High-dose thiamine supplementation may prevent or slow the progression of hyperglycemia toward diabetes mellitus in individuals with impaired glucose regulation.
