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  1. 8 maj 2020 · Diabetes has been found to be associated with low levels of thiamine stores in the body, as thiamine directly affects carbohydrate metabolism. Amplified renal clearance of thiamine has been found in both type I and type II diabetic patients.

  2. 5 cze 2021 · The first reports of a link between thiamine and diabetes date back to the 1940s. Some years later, a role for thiamine deficiency in diabetic neuropathy became evident, and some pilot studies evaluated the putative effects of thiamine supplementation.

  3. The first reports of a link between thiamine and diabetes date back to the 1940s. Some years later, a role for thiamine deficiency in diabetic neuropathy became evident, and some pilot studies evaluated the putative effects of thiamine supplementation.

  4. 31 gru 2019 · Interpretation: Thiamine supplementation does not affect glycaemic outcomes, however reduces triglycerides while increasing HDL. Multicentre well-designed RCT with higher doses of thiamine and a follow-up period of 1–2 years will provide better evidence. PROSPERO registration number CRD42020170520.

  5. 22 lut 2023 · The present systematic review and meta-analysis showed lower systemic concentrations of thiamine, TMP, and total thiamine in individuals with diabetes compared to those without diabetes, while TDP and erythrocyte transketolase activity tended to be lower in the diabetes group without reaching statistical significance.

  6. 29 lut 2024 · The Thiamine as Adjunctive Therapy for Diabetic Ketoacidosis (DKAT) trial was developed to assess the clinical efficacy of intravenous thiamine for reversal of acidosis and improvement of cellular oxygen consumption in patients admitted to the hospital with diabetic ketoacidosis (DKA).

  7. High-dose thiamine supplementation may prevent or slow the progression of hyperglycemia toward diabetes mellitus in individuals with impaired glucose regulation.