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4 maj 2022 · Collectively, genetic studies are providing persuasive evidence that there is underlying genetic liability that predisposes to both SUDs and chronic pain, depression, and COVID-19. For cardiometabolic disease, there is greater support for a potential causal influence of problematic substance use.
Briefly, findings from twin and family studies suggest common genetic factors shared amongst substance use (r g = 0.14–0.31 for alcohol, tobacco, and cannabis), with stronger estimates of shared genetic overlap amongst measures of problem use (r g = 0.56–0.62; Young, Rhee, Stallings, Corley, & Hewitt, 2006).
22 mar 2023 · Breakthrough findings could lead to more effective prevention and treatment strategies for multiple substance use disorders. By combing through genomic data of over 1 million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used. This dataset – one of the largest of its ...
1 wrz 2019 · While use of some substances, such as alcohol, may predispose individuals to cancer, [3] substance use can also develop after a cancer diagnosis in the setting of cancer pain management. Additionally, individuals with cancer may use substances in attempts to cope with psychological distress or poorly-controlled physical symptoms, sometimes ...
Although addiction is multifactorial, heritability estimates have indicated that around 40%–60% of the population variability in becoming addicted to nicotine, alcohol, or illicit drugs is attributable to genetic factors [3, 5]. Some genetic factors may influence an overarching susceptibility to developing addiction; thus, their effects are ...
5 mar 2018 · Some genetic factors may influence an overarching susceptibility to developing addiction; thus, their effects are shared across different drugs of abuse. In contrast, other genetic factors may underlie susceptibility to developing specific drug addictions.
Substance abuse reduces treatment compliance, worsens cancer prognosis and seems to be a negative factor for the quality of life of these patients. Current literature highlights the importance of appropriate psychiatric interventions to address substance abuse in cancer patients.
