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  1. Briefly, findings from twin and family studies suggest common genetic factors shared amongst substance use (r g = 0.14–0.31 for alcohol, tobacco, and cannabis), with stronger estimates of shared genetic overlap amongst measures of problem use (r g = 0.56–0.62; Young, Rhee, Stallings, Corley, & Hewitt, 2006).

  2. The researchers discovered a strong genetic correlation between problematic alcohol use and 138 other conditions, including substance abuse disorders, depression, and schizophrenia. “AUD has many variants across the genome that are involved in the predisposition of this trait, but these variants are not only predisposing to AUD, they are ...

  3. 22 mar 2023 · By combing through genomic data of over 1 million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used.

  4. 23 wrz 2016 · Spice is not a single drug, but a range of laboratory-made chemicals that mimic the effects of tetrahydrocannabinol (THC), the main psychoactive component of cannabis. Research suggests...

  5. 28 sty 2019 · Drugs of abuse, including opioids, act on the brain's reward system, a system that transfers signals primarily via a molecule (neurotransmitter) called dopamine. The function of this system is affected by genetic and environmental factors.

  6. 1 lip 2005 · Genetic loci that have defined roles in addictions include substance-specific genes, such as the alcohol metabolic genes, and loci, such as the serotonin transporter and COMT, that alter...

  7. 1 sie 2009 · Addictive disorders are prevalent in many populations, influenced by genetic and environmental factors, and moderately to highly heritable. Often, addictions to different substances co-occur,...

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