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22 mar 2023 · By combing through genomic data of over 1 million people, scientists have identified genes commonly inherited across addiction disorders, regardless of the substance being used. This dataset – one of the largest of its kind – may help reveal new treatment targets across multiple substance use disorders, including for people diagnosed with ...
The researchers discovered a strong genetic correlation between problematic alcohol use and 138 other conditions, including substance abuse disorders, depression, and schizophrenia. “AUD has many variants across the genome that are involved in the predisposition of this trait, but these variants are not only predisposing to AUD, they are ...
23 wrz 2016 · Spice is not a single drug, but a range of laboratory-made chemicals that mimic the effects of tetrahydrocannabinol (THC), the main psychoactive component of cannabis.
4 maj 2022 · Collectively, genetic studies are providing persuasive evidence that there is underlying genetic liability that predisposes to both SUDs and chronic pain, depression, and COVID-19. For cardiometabolic disease, there is greater support for a potential causal influence of problematic substance use.
The present review will focus on five SUDs that have demonstrated substantial progress in molecular genetics in recent years: alcohol use disorder (AUD), nicotine use disorder (NicUD), cannabis use disorder (CanUD), opioid use disorder (OUD), and cocaine use disorder (CocUD).
1 lip 2005 · Genetic loci that have defined roles in addictions include substance-specific genes, such as the alcohol metabolic genes, and loci, such as the serotonin transporter and COMT, that alter...
18 kwi 2024 · In this post, I provide an overview of key research on the genetic inheritance of substance use disorders such as alcohol use disorder, opioid use disorder, and cannabis/marijuana use disorder.