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Such pathways are not exclusive to AUD. The researchers discovered a strong genetic correlation between problematic alcohol use and 138 other conditions, including substance abuse disorders, depression, and schizophrenia.
23 wrz 2016 · Spice is not a single drug, but a range of laboratory-made chemicals that mimic the effects of tetrahydrocannabinol (THC), the main psychoactive component of cannabis. Research suggests...
The substance use genetics literature is rich with rodent models of addictive behaviors (e.g. positive reinforcement via self-administration paradigms, withdrawal avoidance and drug-seeking).
22 mar 2023 · Dr. Hatoum and the research team discovered various molecular patterns underlying addiction, including 19 independent SNPs significantly associated with general addiction risk and 47 SNPs for specific substance disorders among the European ancestry sample.
28 sty 2019 · As in most cases of psychiatric disorders, genetic and environmental factors interact to determine how vulnerable, or likely, you are to developing a substance use disorder. Drugs of abuse, including opioids, act on the brain's reward system, a system that transfers signals primarily via a molecule (neurotransmitter) called dopamine.
20 wrz 2024 · Drug and alcohol addiction is a complex brain disorder characterized by compulsive substance use despite harmful consequences. There is no single cause, but research has revealed a strong correlation between addiction and genetic factors.
18 kwi 2024 · In this post, I provide an overview of key research on the genetic inheritance of substance use disorders such as alcohol use disorder, opioid use disorder, and cannabis/marijuana use...