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1. www.nejm.org › doi › fullOnce-Weekly Semaglutide in Adults with Overweight or Obesity

   www.nejm.org › doi › full

   10 lut 2021 · Our trial showed that among adults with overweight or obesity (without diabetes), once-weekly subcutaneous semaglutide plus lifestyle intervention was associated with substantial, sustained ...

2. www.thelancet.com › journals › landiaSemaglutide: weighing up the benefits and risks

   www.thelancet.com › journals › landia

   Semaglutide could offer an easier and more reliable way to lose weight and combat the health impacts people with obesity face. Why should this drug, proven to work, not be available to help people change their lives?

3. www.nature.com › articles › s41591/024/02996-7Long-term weight loss effects of semaglutide in obesity without...

   www.nature.com › articles › s41591/024/02996-7

   13 maj 2024 · With semaglutide, lower BMI was associated with less percentage weight loss, and women lost more weight on average than men (−11.1% versus −7.5% treatment difference from placebo);...

4. www.bmj.com › content › 385Semaglutide may provide sustained weight loss for at least ... -...

   www.bmj.com › content › 385

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   16 maj 2024 · A new analysis of data from Novo Nordisk’s Select trial indicates that semaglutide (marketed as Wegovy) can enable patients who are overweight or obese to “achieve clinically meaningful weight loss” for at least four years, with fewer serious adverse events than placebo.1 The analysis, conducted by the manufacturer and published in Nature ...

5. www.ncbi.nlm.nih.gov › pmc › articlesSemaglutide in Obesity: Unmet Needs in Men - PMC - National...

   www.ncbi.nlm.nih.gov › pmc › articles

   7 sty 2023 · The potential benefit of weight loss induced by GLP-1 RA on male sexual function and fertility remains significantly understudied, and the impact of GLP-1 RA on the gonadal axis and on obesity-related hypogonadism in men has been evaluated only in one study .

6. diet.mayoclinic.org › us › blogHow does semaglutide work? - Mayo Clinic Diet

   diet.mayoclinic.org › us › blog

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   Appetite regulation. Semaglutide mimics the natural hormone GLP-1, which is produced in the gut and plays a key role in regulating appetite and food intake. GLP-1 receptors are found in the brain, particularly in the hypothalamus and brainstem, which are involved in controlling hunger and satiety.