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15 lip 2020 · People with coronavirus disease (COVID-19) may frequently require treatment with psychotropic medications, but are at the same time at higher risk for safety issues because of the complex underlying medical condition and the potential interaction with medical treatments.
Clozapine intoxication, pneumonia and delirium are the main complications of COVID-19 in patients on clozapine. In order to prevent clozapine intoxication, reduction of the original dose by half is generally recommended in clozapine users who contract COVID-19.
The case presented here describes a patient with schizophrenia who was being managed on clozapine and who developed symptomatic COVID-19 infection. Special care was taken to ensure that potential interactions between clozapine and the associated COVID-19 treatments were safe for the patient's mental and physical wellbeing.
3 sty 2023 · There was no strong evidence that clozapine users may be at increased risk of contracting COVID-19 or developing complications after adjusting for medical comorbidities. Hematological studies showed temporary reductions in neutrophils in COVID-19-positive patients and vaccination suggesting a clozapine effect in defence against infection.
14 maj 2020 · Those prescribing clozapine must be proactive to coordinate with pharmacies to ensure clozapine therapy continues uninterrupted due to COVID-19 pandemic barriers.
This is likely to arise partly from a higher risk of exposure to COVID-19 in hospital settings, and largely from the policy that in-patients showing any symptoms of COVID-19 were tested, while testing in the community was less comprehensive.
5 gru 2020 · In the context of "COVID-19 anxiety," benzodiazepines such as alprazolam (Xanax), clonazepam (Klonopin), and lorazepam (Ativan) are being widely prescribed.