Search results
Tell your doctor if you are pregnant or planning to become pregnant. Using this medicine during the later pregnancy may cause problems in your newborn baby (eg, sedation or withdrawal symptoms).
While earlier studies suggested an association between prenatal exposure to benzodiazepines and increased risk of cleft lip and palate, more recent studies have not demonstrated any increase in risk of congenital malformations. Recently there have been a series of new.
10 paź 2024 · Diazepam Pregnancy Warnings. This drug should not be used during pregnancy unless the benefit outweighs the risk to the fetus. AU TGA pregnancy category: C US FDA pregnancy category: Not assigned. Risk Summary: An increase in congenital malformations has been suggested with minor tranquilizer use, especially during the first trimester. Comments:
Does taking diazepam in pregnancy increase the chance of other pregnancy-related problems? Some, but not all, studies have reported an increased chance for preterm delivery (delivery before 37 weeks of pregnancy), low birth weight (weighing less than 5 pounds, 8 ounces [2500 grams] at birth), and/or smaller head size in babies born to a person ...
Use of diazepam around term should therefore be avoided unless use can be clinically justified. Exposure to diazepam during pregnancy would not usually be regarded as medical grounds for termination of pregnancy.
A study by Sheehy and colleagues 5 showed that early pregnancy exposure to various benzodiazepines was associated with an increased risk of spontaneous abortion. Huitfeldt and colleagues 6 found a relationship between benzodiazepines or Z-hypnotics use and preterm birth but not birth weight.
3.2. Therapeutic Drug Monitoring in Pregnant Women. TDM is crucial during pregnancy due to physiological changes that can alter drug pharmacokinetics, potentially affecting treatment efficacy and toxicity for both mother and fetus. TDM aims to optimize drug dosing regimens, enhance treatment effectiveness, and minimize toxicity . This approach ...
