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4 dni temu · In this review, we summarize the findings regarding genetic, epigenetic, and environmental risk factors identified in autism, and discuss the issue of gene x environment interactions (GxE).
- Environmental factors influencing the risk of autism - PMC
It has been found that genetic and environmental factors are...
- Genetic Causes and Modifiers of Autism Spectrum Disorder
ASD is now understood to be a disease of complex interaction...
- Environmental factors influencing the risk of autism - PMC
17 maj 2021 · Although the full aetiology of autism spectrum disorder (ASD) is unknown, familial and twin studies demonstrate high heritability of 60–90%, indicating a predominant role of genetics in the ...
16 lut 2017 · It has been found that genetic and environmental factors are both involved in autism pathogenesis. Hence, in this review article, a set of environmental factors involved in the occurrence of autism has been collected, and finally, some practical recommendations for reduction of the risk of this devastating disease in children are represented.
10 wrz 2020 · The complex pathophysiology of autism spectrum disorder encompasses interactions between genetic and environmental factors. On the one hand, hundreds of genes, converging at the functional level on selective biological domains such as epigenetic regulation and synaptic function, have been identified to be either causative or risk factors of autism.
20 sie 2019 · ASD is now understood to be a disease of complex interaction between genetics and the environment, with heritability estimates ranging from 40 to 80% (Chaste and Leboyer, 2012). Extensive genetic studies have revealed hundreds of genes linked to autism.
17 mar 2017 · Findings: Current evidence suggests that several environmental factors including vaccination, maternal smoking, thimerosal exposure, and most likely assisted reproductive technologies are unrelated to risk of ASD. On the contrary, advanced parental age is associated with higher risk of ASD.
20 gru 2018 · Autism spectrum disorder (ASD) is a neurodevelopmental condition of heterogeneous etiology. While it is widely recognized that genetic and environmental factors and their interactions contribute to autism phenotypes, their precise causal mechanisms remain poorly understood.
