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  1. 6 cze 2022 · Iron homeostasis is mainly controlled by intestinal absorption because iron does not have active excretory mechanisms for humans. Thus, efficient intestinal iron bioavailability is essential to reduce the risk of iron deficiency anemia. There are two forms of iron, heme and nonheme, found in foods.

  2. 10 cze 2022 · Because humans do not have an active iron excretion system, intestinal iron absorption is critical for maintaining iron balance in the body. (11) A typical Western diet contains 7 mg of iron per 1000 kcal; however, only 1–2 mg is absorbed daily.

  3. 8 sie 2014 · Iron absorption is precisely regulated by a range of systemic and cellular mediators (Fig. 2). Liver-derived, circulating HEPC regulates duodenal iron absorption and also modulates iron release from stores in hepatocytes and RE macrophages (which recycle iron from senescent erythrocytes).

  4. 1 mar 1998 · This review compiles and discusses current knowledge and hypotheses on the specific biochemical pathways of each of the three steps of iron absorption, i.e., uptake from the intestinal lumen, transit through the cell, and release from the cell to the circulation.

  5. In addition to dietary factors, body iron status is a major determinant of iron absorption. The roles of these important dietary and systemic factors in regulating iron absorption will be discussed in this review.

  6. This article presents a brief overview of the molecular mechanisms of intestinal iron absorption and its regulation. While many proteins that orchestrate iron transport pathway have been identified, a number of key factors that control the regulation of iron absorption still remain to be elucidated.

  7. This article presents a brief overview of the molecular mechanisms of intestinal iron absorption and its regulation. While many proteins that orchestrate iron transport pathway have been identified, a number of key factors that control the regulation of iron absorption still remain to be elucidated.

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