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  1. What Lantus looks like and contents of the pack. Lantus 100 units/ml solution for injection in a vial is a clear, colourless and waterlike solution. Each vial contains 5 ml of solution for injection (equivalent to 500 units) or 10 ml of solution for injection (equivalent to 1000 units).

  2. Each milliliter of LANTUS (insulin glargine injection) contains 100 Units (3.6378 mg) insulin glargine. The 10 mL vial presentation contains the following inactive ingredients per mL: 30 mcg...

  3. Presentations: Lantus 100 units/ml solution for injection in a vial or in a cartridge. Lantus SoloStar 100 units/ml solution for injection in a pre-filled pen. Lantus cartridges and Solostar pre-filled pens each contain 3 ml of solution for injection, equivalent to 300 units insulin glargine. Each vial contains 10 ml of solution

  4. Lantus®, the initial dose was usually not changed (i.e. amount of International Units, IU, of Lantus® per day equal to IU of NPH insulin). In studies when patients were transferred from twice daily NPH insulin to once daily Lantus® at bedtime, to reduce the risk of hypoglycaemia, the initial dose (IU), was usually reduced by approximately 20%

  5. The recommended starting dose of Lantus ® in patients with type 2 diabetes who are not currently treated with insulin is 0.2 Units/kg or up to 10 Units once daily, adjusted to patient’s appropriate FPG target. One may need to adjust the amount and timing of short- or rapid-acting insulins and dosages of any oral anti-diabetic drugs

  6. Lantus SoloStar 100 units/ml in pre-filled pen is only suitable for subcutaneous injections. If administration by syringe is necessary, a vial should be used (see section 4.2). Before using SoloStar, the instructions for use included in the package leaflet must be read carefully.

  7. Solution for injection. Clear colourless solution. Qualitative and quantitative composition. Each ml contains 100 units insulin glargine* (equivalent to 3.64 mg).

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