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powiązane z: interleukin 11 side effects in elderlyBrowse publications for IL-11. Animal free and RUO product grades available.
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18 lip 2024 · When mice were given an anti-IL-11 therapeutic at 75 weeks of age (the equivalent of around 55 human years) until death, the average lifespan of male mice was increased by 22.5% and 25% in...
24 lip 2024 · A protein called interleukin 11 (IL-11) appears to play a crucial role in aging, with scientists extending the lifespans of mice by up to 25 percent simply by blocking the molecule's effects. Could it work in humans?
17 lip 2024 · Interleukin-11 does have a role in the human body during early development. People are, very rarely, born unable to make it. This alters how the bones in their skull fuse together, affects...
17 lip 2024 · The scientists, working with colleagues at Duke-NUS Medical School in Singapore, tested the effects of IL-11 by creating mice that had the gene producing IL-11 (interleukin 11) deleted. This extended the lives of the mice by over 20% on average.
17 lip 2024 · Here we examined whether IL-11, a pro-inflammatory cytokine of the IL-6 family, has a negative effect on age-associated disease and lifespan. As mice age, IL-11 is upregulated across cell types and tissues to regulate an ERK–AMPK–mTORC1 axis to modulate cellular, tissue- and organismal-level ageing pathologies.
16 lip 2024 · In a new paper appearing in Nature, the team demonstrated in preclinical mouse studies that the protein interleukin-11 (IL11) actively promotes aging, and that giving an anti-IL11 therapy not only counteracts the deleterious effects of aging but also increases lifespan.
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powiązane z: interleukin 11 side effects in elderlyBrowse publications for IL-11. Animal free and RUO product grades available.