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2 maj 2022 · Excipients used in oral dosage forms are traditionally viewed as inert ingredients that aid in the practical aspects of a formulation. Examples of these excipients include bulking agents, fillers, disintegrants, and substances that affect tablet hardness and taste.
2 mar 2022 · We highlight the lack of mitigation in place to protect bees from ‘inert’ ingredients and argue that research efforts should be redistributed to address the knowledge gap identified here. If so-called ‘inert’ ingredients are, in fact, detrimental to bee health, their potential role in widespread bee declines needs urgent assessment.
24 lip 2020 · Inactive ingredients may not be inert. Most drug formulations comprise mainly inactive ingredients known as excipients. Excipients are tested in animal studies and do not display toxicity at allowed concentrations, but their interaction with molecular targets has not been systematically explored.
25 cze 2020 · The number of inactive ingredients in the 230 analyzed formulations ranged from 1 to 14 (median = 4) with only five biological products containing 10 or more excipients (Fig 2). The most common inactive ingredients are water (40.4%), sodium chloride (38.3%), polysorbate 80 (28.7%), and sucrose (24.3%), occurring in over 50 formulations.
29 lip 2020 · The secret life of excipients. Katie Kingwell. In addition to the active pharmaceutical ingredient, drug formulations contain excipients such as stabilizers, colourants and antioxidants, which...
18 sie 2006 · Inert ingredients are often biologically or chemically active and can affect each of these parameters. Demonstrations of important impacts of inert ingredients have not been limited to particular classes of pesticides, types of formulations, or toxicity end points.
1 kwi 2021 · Biopharmaceutical interactions occur after drug administration and mainly affect the pharmacokinetics of the drugs. All these interactions will be defined and explained through the many...
