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30 mar 2022 · The efficacy of ivermectin in preventing hospitalization or extended observation in an emergency setting among outpatients with acutely symptomatic coronavirus disease 2019 (Covid-19), the...
- Original Article Two Phase 3 Trials of Baricitinib for Alopecia Areata B. King and Others
Alopecia areata is an autoimmune condition characterized by...
- Images in Clinical Medicine Primary Cutaneous Blastomycosis A. Alhatem and K.C. Smith
A 53-year-old landscaper presented with a 4-month history of...
- Perspective Real-World Evidence — Where Are We Now J. Concato and J. Corrigan-Curay
Notwithstanding ongoing confusion over the concepts of...
- Clinical Practice Nonspecific Low Back Pain A. Chiarotto and B.W. Koes
Nonspecific low back pain is diagnosed by ruling out other...
- Editorial Baricitinib in Alopecia Areata A. Messenger and M. Harries
Scalp hair regrowth is associated with improvements in...
- Clinical Problem-Solving Looking Back L. Glick and Others
The creatinine level was 2.6 mg per deciliter (230 μmol per...
- Original Article Two Phase 3 Trials of Baricitinib for Alopecia Areata B. King and Others
14 gru 2022 · Given the wide availability and low cost of ivermectin and that the dosage used in the trial appeared to be safe, such treatment effects could be an important benefit for high-risk patients...
Ravikirti, Roy R, Pattadar C, Raj R, Agarwal N, Biswas B, Manjhi PK, et al. Evaluation of ivermectin as a potential treatment for mild to moderate COVID-19: a double-blind randomized placebo controlled trial in Eastern India.
Methods: A double blind, parallel, randomised, placebo-controlled trial conducted among adult COVID-19 patients with mild to moderate disease severity on admission in a COVID dedicated tertiary healthcare of eastern India. Enrolment was done between 1st August and 31st October 2020.
We evaluated the effects of ivermectin in infected people on: people dying; whether people's COVID-19 symptoms got better or worse; unwanted effects; hospital admission or time in hospital; viral clearance. For prevention, we sought the effect on preventing COVID-19 and SARS-CoV-2 infection.
16 lut 2021 · Two-dose ivermectin prophylaxis at a dose of 300 μg/kg with a gap of 72 hours was associated with a 73% reduction of SARS-CoV-2 infection among healthcare workers for the following month. Chemoprophylaxis has relevance in the containment of pandemic.
26 lip 2021 · In this study, single addition of 5 μM Ivermectin to Vero-hSLAM cells 2 h post infection with SARS-CoV-2 demonstrated ∼5000-fold reduction in viral RNA at 48 h. 7 The anti-viral mechanism of Ivermectin in COVID-19 is attributed to inhibition of the importin (IMP) α/β receptor, which is responsible for transmitting viral proteins into the ...