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For example, the effects of in utero alcohol exposure differ between inbred and selectively bred mice. These findings highlight the contribution of a genetic predisposition to the susceptibility to the detrimental effects of prenatal ethanol exposure and provide additional support for the importance of genetic factors in the development of FASD ...
17 paź 2022 · Alcohol outcomes in the child generation included lifetime criterion counts for DSM-5 Alcohol Use Disorder (AUD), lifetime maximum drinks in 24 h, age at initiation of regular drinking,...
26 lip 2023 · Fetal alcohol spectrum disorders (FASD) are the leading preventable neurodevelopmental disorders and two hallmark symptoms of FASD are abnormal behavior, and cognitive and learning deficits. The severity of alcohol’s teratogenic effects on the developing brain is influenced by genetics and sex.
There was a significant increased risk of abnormal or borderline scores on the peer problems scale for children not exposed to alcohol compared to children to a cumulative 15–45 drinks over the pregnancy (Boys: RCM 1.21, 95% CI [1.03, 1.43]; Girls: RCM 1.40, 95% CI [1.15, 1.71]).
The adoption study compares the risk of alcoholism in biological relatives with the risk in adoptive relatives of alcoholics (e.g., an adopted-away child of an alcoholic parent). In contrast, the twin study compares the risk of alcoholism in identical and fraternal pairs of twins reared in the same environment.
1 sty 2022 · Animal and human studies have demonstrated prenatal alcohol-related alterations in methylation and expression of imprinted genes that appear to partly mediate effects of alcohol on placental, fetal, and postnatal growth.
27 wrz 2024 · Fetal alcohol spectrum disorder (FASD) describes a group of permanent symptoms experienced by people who were exposed to alcohol in utero (during pregnancy). There are currently five conditions that make up FASD, including fetal alcohol syndrome (FAS).
