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22 gru 2022 · The researchers found that inbreeding in humans causes physical and mental problems, though the severity of those effects was somewhat limited. The average for the seven traits that inbreeding negatively impacted in the study was between 0.3 and 0.7 standard deviations below the mean.
Addiction research in inbred, or isogenic, mouse lines has demonstrated genetic contributions to nicotine and alcohol abuse- and addiction-related behaviors.
17 lip 2012 · This selective review outlines and highlights the need for a multi-method translational approach to genetic studies of these important conditions, including both licit (alcohol, nicotine) and ...
1 lip 2022 · This review summarizes inbred mouse strain differences in alcohol and nicotine addiction-related phenotypes including voluntary consumption/self-administration, initial sensitivity to the drug as measured by sedative, hypothermic, and ataxic effects, locomotor effects, conditioned place preference or place aversion, drug metabolism, and ...
14 paź 2014 · This study is one of the first attempts with details of inbreeding coefficients and elaborate statistics to examine the effects of inbreeding on the cognitive abilities of children among the indigenous Muslim populations of Jammu region (Northern India).
1 lip 2005 · Key Points. Addictions are common chronic psychiatric diseases that are characterized by persistent, compulsive and uncontrolled use. Addictions are a worldwide public-health issue, causing 12.4%...
25 kwi 2018 · Neurobiology Of Addiction Risk. The risk for addiction is related to complex interactions between biological factors (genetics, epigenetics, developmental attributes, neurocircuitry) and environmental factors (social and cultural systems, stress, trauma, exposure to alternative reinforcers).