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Inbreeding depression is ubiquitous, but we still know little about its genetic architecture and precise effects in wild populations. Here, we combine long-term life-history data with 417 K imputed SNP genotypes for 5952 wild Soay sheep to explore inbreeding depression on a key fitness component, annual survival.
6 mar 2024 · Early-acting inbreeding depression should increase with the primary selfing rate (up to a point). The greater the risk of inadvertent selfing, the greater the benefit of adaptive early-acting inbreeding depression.
Inbreeding depression, the reduction of fitness caused by inbreeding, is a nearly universal phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates suggest that its impact on individual fitness is even greater than previously thought.
14 paź 2014 · The negative sign for r-value indicates the depression in cognitive tests with the increasing levels of inbreeding. The regression analysis strongly supports the evidence of inbreeding depression on child’s verbal, performance and full intellectual skills.
1 kwi 2010 · Which genes or functional classes of genes are responsible for the decrease in fitness associated with inbreeding? What is the underlying cause of inbreeding depression, overdominance or partially recessive deleterious alleles? How does environment influence gene expression associated with inbreeding and inbreeding depression?
17 sie 2016 · This phenomenon, known as inbreeding depression, can be caused by increased homozygosity at loci with deleterious recessive alleles, or decreased heterozygosity at loci displaying heterozygous advantage (Charlesworth & Willis, 2009).
12 sty 2021 · We found that inbreeding depression severely impacted multiple life-history stages, and directly translated into an effect on population viability under management alternatives.
