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  1. How do therapeutic agents perform when compared to each other to allow a tiered approach to treating patients with COVID-19? What is the comparative efficacy and safety of nirmatrelvir/ritonavir versus remdesivir, molnupiravir, and different anti-SARS-CoV-2 antibodies in mild-to-moderate disease?

    • Paxlovid

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    • Antigen Testing

      December 20, 2022. Version 2.0.0 has been released and...

    • Serology

      Serologic tests for severe acute respiratory syndrome...

    • Training and Resources

      The primary objective of clinical practice guidelines is to...

  2. 29 lis 2023 · Immunological senescence and inflammation play a severe role in contributing to older patients who are more prone to severe outcomes of COVID-19 (1, 3). IgG antibodies, also known as immunoglobulin G, offer a prominent means of protection against contagious illnesses.

  3. Our results suggested that the decline of IgM may be an indicator of virus clearance and recovered patients may have a robust immunity against reinfection within at least 3 months after illness onset.

  4. 1 cze 2022 · Hydroxychloroquine, dexamethasone, and remdesivir revealed greater side effects or inefficiency in geriatric patients with COVID-19. Favipiravir, bamlanivimab, baricitinib, and supportive therapy showed a decrease in viral load and improvement of clinical symptoms.

  5. 29 kwi 2020 · Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG...

  6. The peak of IgG is higher from the young group (18–45 years old) at 4.968 (+1.609, −1.609) S/CO and existed for a longer time (about 2 weeks), while the elderly group (>60 years old) has a lower peak of IgG level at 3.675 (+2.423, −2.423) S/CO and a shorter time (about 1 week), which may be associated with the depression of immunity in ...

  7. Strikingly, IgM-14 was more potent than IgG-14 in neutralizing SARS-CoV-2 VOCs, including Alpha, Beta and Gamma variants, as well as 21 other RBD mutants, indicating that IgM-14 is superior to IgG-14 in covering viral escape mutations.

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