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1 kwi 2019 · Although a rare disease, aplastic anemia should be distinguished from other cases of pancytopenia, and patients should receive the best treatment available based on their age, and the existence of a matched sibling donor.
Severe aplastic anaemia is a rare haematological disorder characterized by severe pancytopenia in the peripheral blood and a hypocellular bone marrow. Immunosuppressive therapy (IST) and haematopoietic stem cell transplantation (HSCT) are the main treatment modalities, and although the
1 kwi 2019 · Current concepts in the pathophysiology and treatment of aplastic anemia. Hematol Am Soc Hematol Educ Program 2013;2013 (1);76–81. Solomou, EE, Keyvanfar, K, Young, NS. T-bet, a Th1 transcription factor, is up-regulated in T cells from patients with aplastic anemia.
10 gru 2011 · Mainstays for treatment for aplastic anemia remain HSCT, the only curative therapy to date, and immunosuppressive therapy (IST).
22 cze 2021 · Establishing a diagnosis of aplastic anemia (AA) can be challenging, but it is absolutely critical to appropriate management, especially differentiating between acquired and inherited forms of the disease.
11 lis 2017 · Aplastic anemia (AA) is a rare, immune-mediated hematopoietic disorder associated with significant morbidity and mortality. In patients with suspected AA, rapid and accurate diagnosis and concomitant supportive care are critical.
16 mar 2017 · First-line treatment for severe aplastic anemia in children: bone marrow transplantation from a matched family donor versus immunosuppressive therapy.
