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HIV-positive women have higher human papillomavirus (HPV) prevalence and cervical cancer (CC) incidence than HIV-negative women, partly due to HIV’s modifying effect on HPV pathogenesis. We synthesized the literature on the impact of HIV on HPV natural history.
27 mar 2018 · HIV-positive women have higher risk of acquiring HPV, with risk inversely associated with CD4 cell count. ART lowered HPV acquisition, increased clearance, and reduced precancer progression, likely via immune reconstitution.
15 gru 2022 · In addition to many barriers in access to human papillomavirus vaccination and cervical screening, these women face a substantially higher risk of persistent hrHPV infection.17 18 19 Women living with HIV are also more likely to be diagnosed as having cervical cancer or cervical pre-cancer.20
26 kwi 2024 · HPV infection disproportionally affects individuals living with HIV, resulting in decreased clearance, increased development of cancer, and increased mortality. The development of the HPV vaccine has shown a drastic decrease in HPV-related diseases.
1 gru 2022 · Cervical cancer elimination in WLHIV would likely require enhanced prevention strategies for WLHIV. Screening of WLHIV remains an important strategy to reduce incidence and alleviate disparities in cervical cancer burden between women with and without HIV, despite HIV interventions scale-up.
16 lis 2020 · Women living with HIV have a significantly increased risk of cervical cancer. HPV vaccination and cervical cancer screening for women living with HIV are especially important for countries in southern Africa and eastern Africa, where a substantial HIV-attributable cervical cancer burden has added to the existing cervical cancer burden.
22 kwi 2020 · This study shows limited evidence on the interaction of HIV and HPV-related cancers especially on anal cancer across all genders, vaginal cancer, vulvar cancer, head and neck cancers, and penile cancer.