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Concurrently, experimental studies in murine model of ischemic stroke demonstrated that HIV infection worsens stroke outcome, increases blood brain barrier permeability and increases neuroinflammation.
1 maj 2019 · Using the EcoHIV infection model and the middle cerebral artery occlusion as the ischemic stroke model in mice, we present in vivo analysis of the relationship between HIV and stroke outcome....
HIV infection can result in stroke via several mechanisms, including opportunistic infection, vasculopathy, cardioembolism, and coagulopathy. However, the occurrence of stroke and HIV infection might often be coincidental. HIV-associated ...
HIV infection and the middle cerebral artery occlusion (MCAO) model enabled us to directly evaluate post-ischemic stroke injury progression and recovery in HIV-infected brain. Our results
Recent research indicates that people with HIV on suppressive ART still sustain persistent, albeit alleviated, systemic and cerebral immune activation that can facilitate age-related causes of cognitive impairment (CI), including neurodegenerative and cerebrovascular diseases.
HIV is thought to increase the risk of stroke through both HIV-related and traditional stroke risk factors, which vary with respect to the patient’s age and clinical characteristics. Numerous studies show that detectable viremia and immunosuppression increase the risk of stroke across all ages while traditional risk factors are more common in ...
11 wrz 2003 · In our view, physicians caring for HIV-infected individuals with stroke need to formulate 2 important questions: (1) Is a spinal tap indicated, and (2) does the patient have a coagulopathy? Mochan et al reported a cohort of 33 patients with cerebral infarction and 2 with primary intracerebral hemorrhage.
