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HPV infection and HIV acquisition in women. Averbach[], Low[] and Smith-McCune[] et al increased risk of HIV acquisition associated with infection with any HPV genotype compared to no HPV infection in women.The point estimate from all three were consistent with a harmful effect of HPV infection (aHR=1.71, aHR=2.40 and aHR=2.26 respectively) although the association was only statistically ...
- HPV and the Risk of HIV Acquisition in Women - PMC - PubMed Central (PMC)
Here we review current insights into how HPV infection and...
- HPV and the Risk of HIV Acquisition in Women - PMC - PubMed Central (PMC)
Abstract. HIV-related immunodeficiency has complex effects on female genital HPV, which include increased risks of infection, multiple types, persistence, reactivation and the risk to develop pre-invasive and invasive disease.
1 lut 2018 · HIV-related immunodeficiency has complex effects on female genital HPV, which include increased risks of infection, multiple types, persistence, reactivation and the risk to develop pre-invasive and invasive disease.
Several studies have reported an increased risk for HPV infection in PLWH receiving more advanced immune suppression such as those affected by AIDS-defining diseases or profound CD4 depletion (i.e., CD4 counts < 200 cells/µL). However, the heterogeneity and cross-sectional design of most of the studies might limit these conclusions.
Here we review current insights into how HPV infection and the generation of anti-HPV immunity contribute to higher HIV transmission rates, and the impact of HPV on mucosal inflammation, immune cell trafficking, and epithelial barrier function.
5 cze 2018 · The main associations of interest were the relative risk (RR) of acquiring a new HPV infection or clearing an existing HPV infection (outcomes) by HIV serostatus (exposure) (review 1), and the RR of acquiring HIV infection (outcome) by HPV status (either prevalent, recent/incident or recently cleared HPV infection) (exposure) (review 2).
These results provide evidence for synergistic HIV and HPV interactions of clinical and public health relevance. HPV vaccination may directly benefit PLHIV, and help control both HPV and HIV at the population level in high prevalence settings.
