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Misoprostol tablets can be used either in the vagina, or under the tongue (sublingual). You and your doctor will discuss the best option for you. Using misoprostol in the vagina. Misoprostol tablets should be placed deep into the vagina two hours before your planned admission time. 1.
The beneficial effects on cervical ripening may make misoprostol a desirable agent for helping cervical dilatation on non pregnant women also. A few studies are available on the use of misoprostol as cervical priming agent before gynaecological procedures on non pregnant women.
In our study, we used 400 μg single dose of misoprostol by vaginal route 6 h prior to the procedures as a cervical priming agent. Our aim was to see the effectiveness of misoprostol by this approach. Though diagnostic hysteroscopy could be done using 4 mm scope without anesthesia in many cases.
How to Insert the Misoprostol: 1. Empty your bladder. 2. Wash your hands. 3. Push the four misoprostol tablets one at a time up into the vagina as far as you can using your finger. 4. Your health care provider may recommend that you lie down for about 30 minutes after you insert the misoprostol.
Abstract. Study objective: To evaluate the optimal dose of vaginal misoprostol (200 and 400 µg) for cervical priming before operative hysteroscopy. Design: A randomized, controlled, double-blind trial (Canadian Task Force classification I). Setting: A university hospital. Patients: Sixty-eight patients undergoing operative hysteroscopy.
Cervical priming with misoprostol has shown to facilitate transcervical procedures and to reduce side-effects. Cervical priming is recommended by several evidence-based guidelines prior to surgical abortion, dilatation and curettage, hysteroscopy and intrauterine device insertion.
Figure 1: Safe single doses of vaginal misoprostol for producing uterine contractions at various gestations. For the first trimester 800µcg 24 hourly can be safely used. In the second trimester 200µcg 12 hourly is a common dose, whilst beyond 24 weeks 25µcg 6 hourly is usually used.
