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Diagnosis of HSV typically involves detecting the whole virus or viral proteins, genetic materials, or HSV-specific antibodies in the blood. The conventional diagnostic strategies include viral culture, serological tests, and molecular techniques [25, 26].
- The laboratory diagnosis of herpes simplex virus infections
A clinical diagnosis of genital herpes should always be...
- Innate Immune Mechanisms and Herpes Simplex Virus Infection and Disease ...
In this article we will review the innate immune mechanisms...
- The laboratory diagnosis of herpes simplex virus infections
A clinical diagnosis of genital herpes should always be confirmed by laboratory testing; this can be accomplished through the use of direct tests for viral isolation, the detection of antigen or, more recently, the detection of HSV DNA using molecular diagnostic techniques.
The transmission of herpes simplex virus (HSV) infection is dependent upon intimate, personal contact of a susceptible seronegative individual with someone excreting HSV. Virus must come in contact with mucosal surfaces or abraded skin for infection to be initiated.
In this article we will review the innate immune mechanisms that are known to impact HSV infection, the evasion strategies utilized by HSV to over come these responses, and the disease manifestations that result from immune deficiencies. There are two species of HSV, HSV-1 and HSV-2.
Here we review the HSV life cycle, the interaction of HSV with the immune system and three of the best-studied pathologies: Herpes stromal keratitis, herpes simplex encephalitis and genital herpes. We also discuss the potential association between HSV-1 infection and Alzheimer's disease.
2 cze 2021 · Herpes can be diagnosed in two ways, by either detecting the presence of the virus in lesions or the antibodies in the blood. Different detection techniques are available based on both laboratory and point of care (POC) devices.
1 wrz 2006 · This article examines current views on the mechanisms of retrograde and anterograde transport of the virus in axons and the mechanisms of innate and adaptive immunity that control infection in the skin or mucosa and in the dorsal root ganglion—in particular, the role of interferons, myeloid and plasmacytoid dendritic cells, CD4 + and CD8 + T ...
