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  1. Exposure to 7-53 ppm aniline vapor causes slight symptoms after several hours, and concentrations greater than 100-160 ppm cause serious disturbances. As little as 1 g of ingested aniline can be fatal to humans, the mean lethal dose is 5-30 g (HSDB 2000).

  2. On the basis of induction of tumors of the spleen and the body cavity in two studies with rats, U.S. EPA (1994) in their IRIS document classified aniline as B 2, a probable human carcinogen. Evidence is inadequate in humans and sufficient in animals.

  3. 10 sie 2022 · Aniline can be absorbed into the body via inhalation, ingestion or skin contact. It damages red blood cells causing a blood disorder known as methaemoglobinaemia.

  4. Aniline damages hemoglobin, a protein that normally transports oxygen in the blood. The damaged hemoglobin can not carry oxygen. This condition is known as methemoglobinemia and its severity depends on how much you are exposed to and for how long.

  5. 15 lis 2023 · Toxicity: Aniline is considered toxic and can cause adverse health effects upon exposure. Skin Absorption: It can be absorbed through the skin, leading to skin irritation, dermatitis, and systemic effects. Respiratory Effects: Inhalation of aniline vapors or dust can result in respiratory irritation, coughing, and shortness of breath.

  6. The main effect of aniline by any route of exposure is a blood disorder in which oxygen delivery to the tissues is impaired. This may have mild to severe consequences depending on the duration and amount of exposure. Acute exposure to high amounts of aniline may lead to coma and death.

  7. Affected Organ Systems: None. Cancer Classification: Please contact NTP, IARC, or EPA with questions on cancer and cancer classification. Chemical Classification: None. Summary: Aniline is a clear to slightly yellow liquid with a characteristic odor.

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