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3 dni temu · The INTERLACE trial was a multicentre, randomised phase 3 trial done at 32 medical centres in Brazil, India, Italy, Mexico, and the UK. Adults (aged ≥18 years) with locally advanced cervical cancer (FIGO 2008 stage IB1 disease with nodal involvement, or stage IB2, IIA, IIB, IIIB, or IVA disease) were randomly assigned (1:1), by minimisation, using a central electronic system, to standard ...
Management includes fertility sparing treatment, early and locally advanced cervical cancer, invasive cervical cancer diagnosed on a simple hysterectomy specimen, cervical cancer in pregnancy, rare tumors, recurrent and metastatic diseases.
17 paź 2012 · To compare different types and combinations of cytotoxic chemotherapy for the treatment of metastatic/recurrent cervical cancer. Search methods.
8 sie 2023 · In addition to chemotherapy and radiation, therapeutic strategies for cervical cancer include immune checkpoint blockade, antiangiogenics, and antibody-drug conjugates.
30 lip 2024 · According to current guidelines, definitive radiotherapy with concomitant chemotherapy represents the gold standard for locally advanced cervical cancer treatment. However, a significant number of patients relapse and die from metastatic disease.
For patients with metastatic, progressive, and recurrent disease, treatment typically consists of combination chemotherapy and incorporation of bevacizumab, and recent data show benefits with the addition of upfront immunotherapy in women whose cancer expresses programmed death ligand-1.
1 cze 2022 · Chemotherapy is an integral part of the standard cervical cancer treatment regimen and is typically administered as an adjuvant therapy following surgery when poor prognostic tumour features increase the risk of recurrent disease, in combination with radiotherapy as previously mentioned, and as a standalone treatment for locally advanced ...
