Search results
4 cze 2021 · Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), frequently arising from chronic liver diseases.
Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), frequently arising from chronic liver diseases.
10 paź 2020 · Portal hypertension and bleeding from gastroesophageal varices is the major cause of morbidity and mortality in patients with cirrhosis. Portal hypertension is initiated by increased intrahepatic vascular resistance and a hyperdynamic circulatory state.
The primary cause of portal hypertension in cirrhosis is an increase in intrahepatic vascular resistance due to massive structural changes associated with fibrosis and increased vascular tone in the hepatic microcirculation.
Portal hypertension (PH) is a consequence of cirrhosis and an important determinant of its disease course and prognosis. 8–10 In the compensated stage, the development of clinically significant portal hypertension (CSPH), defined by a hepatic venous pressure gradient (HVPG) of at least 10 mmHg, heralds the formation of portal-systemic collateral...
4 cze 2021 · Portal hypertension, defined as increased pressure in the portal vein, develops as a consequence of increased intrahepatic vascular resistance due to the dysregulation of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs), frequently arising from chronic liver diseases.
1 lip 2024 · Cirrhotic portal hypertension is the direct consequence of increased intrahepatic vascular resistance to blood flow, as defined by Ohm's law. 7 Prolonged liver damage triggers a cascade of structural and dynamic alterations that disrupt the hepatic microcirculation and, consequently, these changes are the primary instigators of portal hypertensi...
