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Hippocampal injury can manifest from numerous causes, which comprise head trauma, ischemia, hemorrhagic stroke, acute seizures, status epilepticus (SE), encephalitis, brain tumors, drug withdrawal, exposure to chronic unpredictable stress, and Alzheimer’s disease (AD) [8–12].
- Decoding Hippocampal Signaling Deficits after Traumatic Brain Injury
Sun DA, Deshpande LS, Sombati S, Baranova A, Wilson MS, Hamm...
- Hippocampus in health and disease: An overview - PMC
Hippocampus is a complex brain structure embedded deep into...
- Hippocampal Neurophysiologic Changes after Mild Traumatic Brain Injury ...
Traumatic brain injury (TBI) is the leading cause of death...
- Hippocampal injury-induced cognitive and mood dysfunction, altered ...
Damage to the hippocampus can occur through many causes...
- Decoding Hippocampal Signaling Deficits after Traumatic Brain Injury
Sun DA, Deshpande LS, Sombati S, Baranova A, Wilson MS, Hamm RJ, et al. Traumatic brain injury causes a long-lasting calcium (Ca2+)-plateau of elevated intracellular Ca levels and altered Ca2+ homeostatic mechanisms in hippocampal neurons surviving brain injury.
Hippocampus is a complex brain structure embedded deep into temporal lobe. It has a major role in learning and memory. It is a plastic and vulnerable structure that gets damaged by a variety of stimuli. Studies have shown that it also gets affected in a variety of neurological and psychiatric disorders.
18 cze 2024 · Traumatic brain injury (TBI) can result in long-lasting changes in hippocampal function. The changes induced by TBI on the hippocampus contribute to cognitive deficits. The adult hippocampus...
26 wrz 2018 · Our biophysical measures support the hypothesis that, in the adult brain, peripheral injury is linked to significant extracellular alterations of the ECM at the structural level.
9 lut 2016 · Traumatic brain injury (TBI) is the leading cause of death and disability in individuals below age 45, and five million Americans live with chronic disability as a result. Mild TBI (mTBI), defined as TBI in the absence of major imaging or histopathological defects, is responsible for a majority of cases. Despite the lack of overt morphological ...
Damage to the hippocampus can occur through many causes including head trauma, ischemia, stroke, status epilepticus, and Alzheimer's disease. Certain changes such as increased levels of neurogenesis and elevated concentrations of multiple neurotrophic factors that ensue in the acute phase after inju ….
