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22 lis 2011 · Based on the 99th percentile rule, troponin decision limits of several high-sensitivity cTn assays can be set as low as 0.01 ng/mL. 6 This makes it possible to identify patients with ACS earlier, enabling earlier coronary intervention (Figure 2).
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- Universal Definition of Myocardial Infarction
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High-sensitivity troponin (hs-troponin) assays have been adopted in most hospitals. The definition of high-sensitivity assays is that it is able to detect troponin in healthy subjects without myocardial injury (i.e a few nanograms of troponin per liter blood).
1 mar 2021 · High-sensitivity cardiac troponin (hs-cTn) assays have the ability to detect minute troponin concentrations and resolve minor changes in biomarker concentrations.
14 lip 2022 · This primer discusses the use of high-sensitivity cardiac troponin (hs-cTn) testing in context of the 2021 multisociety guidelines for the evaluation and diagnosis of acute chest pain, with a notable focus on analytical aspects of the hs-cTn assays and their implications.
19 lip 2018 · Denver Health High Sensitivity Troponin (hs-cTn) Web App. This hs-troponin calculator is specific to the evaluation of acute coronary syndromes in the emergency department at Denver Health Medical Center and should not be used outside of this institution and setting.
With that single troponin value, the HEART Score has a NPV >98%. A recent study by Mahler et. al. shows that HEART ≤3 with 2 sets of negative troponin has a NPV of >99% for MACE. Of course, every decrease in risk of endpoints is desirable, but HEART with a single troponin is already a very reliable predictor of MACE/ACS.
Based on the 99th percentile rule, troponin decision limits of several high-sensitivity cTn assays can be set as low as 0.01 ng/mL.6 This makes it possible to identify patients with ACS earlier, enabling earlier coronary inter-vention (Figure 2).
