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22 lis 2011 · The latest generation of high-sensitivity cTn assays can detect cTn in >95% of a reference population. 4 The ability to detect cTns in healthy individuals made it imperative to define a clinical decision limit for cTn concentration, ie, a “positive” cTn result.
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The clinician must interpret cTn re-sults in the context of...
- Universal Definition of Myocardial Infarction
Blood samples for the measurement of troponin should be...
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27 wrz 2024 · Here’s a chart that outlines normal levels of high-sensitivity troponin (hs-troponin), which is used to detect heart injury with greater accuracy than conventional tests. The reference ranges can slightly vary depending on the specific assay used and the population studied.
High-sensitivity troponin (hs-troponin) assays have been adopted in most hospitals. The definition of high-sensitivity assays is that it is able to detect troponin in healthy subjects without myocardial injury (i.e a few nanograms of troponin per liter blood).
1 lip 2022 · A low score (<3) predicts 30-day MACE miss rate within a range of 0% to 2%. In adult patients with recurrent, low-risk chest pain for >3 hours duration, we suggest a single, high-sensitivity troponin below a validated threshold to reasonably exclude ACS within 30 days.
14 lip 2022 · This primer discusses the use of high-sensitivity cardiac troponin (hs-cTn) testing in context of the 2021 multisociety guidelines for the evaluation and diagnosis of acute chest pain, with a notable focus on analytical aspects of the hs-cTn assays and their implications.
The clinician must interpret cTn re-sults in the context of clinical history, ECG findings, and possibly cardiac imaging to establish the correct diag-nosis. A positive troponin in the setting of a low pretest probability for ACS may be suggestive but clearly is not indicative of a coronary event.
Hs-TnI assays allows for more accurate and precise troponin results at very low levels, which permits for the use of an accelerated chest pain algorithm for rapid rule-out/rule-in of AMI. The new hs-TnI reporting protocol will involve reporting results in ng/L (compared to the previous μg/L).