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22 lis 2011 · Based on the 99th percentile rule, troponin decision limits of several high-sensitivity cTn assays can be set as low as 0.01 ng/mL. 6 This makes it possible to identify patients with ACS earlier, enabling earlier coronary intervention (Figure 2).
14 lip 2022 · This primer discusses the use of high-sensitivity cardiac troponin (hs-cTn) testing in context of the 2021 multisociety guidelines for the evaluation and diagnosis of acute chest pain, with a notable focus on analytical aspects of the hs-cTn assays and their implications.
25 kwi 2017 · Schematic representation of five variations of rule-out strategies using high-sensitivity assays for troponin (hsTn) and the key concepts that underlie each element.
1 lip 2022 · Analytical considerations in deriving 99 th percentile upper reference limits for high-sensitivity cardiac troponin assays: educational recommendations from the IFCC committee on clinical application of cardiac bio-markers [published online June 18, 2022].
28 mar 2022 · High-sensitivity troponin assays are used to detect troponins, but at a much lower concentration than classical assays. These assays offer several advantages, first of all being the fact that they are highly sensitive, thus providing faster recognition of AMI (rule-in/rule-out).
Hs-TnI assays allows for more accurate and precise troponin results at very low levels, which permits for the use of an accelerated chest pain algorithm for rapid rule-out/rule-in of AMI. The new hs-TnI reporting protocol will involve reporting results in ng/L (compared to the previous μg/L).
Overall analyses included 10,402 measurements from 1,301 individuals (median [range] age, 48 years [21-89]; body mass index, 25.8 kg/m2 [17.0-56.4]; systolic blood pressure, 122 mmHg [88-140]); sex-specific analyses included 5,248 measurements from 656 women and 5,154 measurements from 645 men.