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  1. 14 lip 2022 · This primer discusses the use of high-sensitivity cardiac troponin (hs-cTn) testing in context of the 2021 multisociety guidelines for the evaluation and diagnosis of acute chest pain, with a notable focus on analytical aspects of the hs-cTn assays and their implications.

  2. 22 lis 2011 · Based on the 99th percentile rule, troponin decision limits of several high-sensitivity cTn assays can be set as low as 0.01 ng/mL. 6 This makes it possible to identify patients with ACS earlier, enabling earlier coronary intervention (Figure 2).

  3. 1 lip 2022 · High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain.

  4. make important recommendations that include the recognition of high-sensitivity cardiac troponin (hs-cTn) as the preferred biomarker, endorsement of 99th percentile upper reference limits to define myocardial injury, and the use of clinical decision

  5. 28 mar 2022 · High-sensitivity troponin assays are used to detect troponins, but at a much lower concentration than classical assays. These assays offer several advantages, first of all being the fact that they are highly sensitive, thus providing faster recognition of AMI (rule-in/rule-out).

  6. The delta (or rate of rise) of repeat troponins over 1-3 hours is important in interpreting detectable troponins. Rapidly rising OR falling troponins outside of the Delta threshold are indicative of myocardial injury even if below the 99th percentile. Delta 0-15 ng/L (up OR down) – Approximately 20% of 99th%ile.

  7. 1 mar 2021 · High-sensitivity cardiac troponin (hs-cTn) assays have the ability to detect minute troponin concentrations and resolve minor changes in biomarker concentrations.