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22 lis 2011 · These levels used to be considered indicative of myocardial necrosis. However, with high-sensitivity troponin assays, circulating cTnT or cTnI can be found in the plasma as a result of transient ischemic or inflammatory myocardial injury.
make important recommendations that include the recognition of high-sensitivity cardiac troponin (hs-cTn) as the preferred biomarker, endorsement of 99th percentile upper reference limits to define myocardial injury, and the use of clinical decision pathways, as well as acknowledgment of the uniqueness of women and other patient subsets.
14 lip 2022 · This primer discusses the use of high-sensitivity cardiac troponin (hs-cTn) testing in context of the 2021 multisociety guidelines for the evaluation and diagnosis of acute chest pain, with a notable focus on analytical aspects of the hs-cTn assays and their implications.
1 lip 2022 · Analytical considerations in deriving 99 th percentile upper reference limits for high-sensitivity cardiac troponin assays: educational recommendations from the IFCC committee on clinical application of cardiac bio-markers [published online June 18, 2022].
28 mar 2022 · High-sensitivity troponin assays are used to detect troponins, but at a much lower concentration than classical assays. These assays offer several advantages, first of all being the fact that they are highly sensitive, thus providing faster recognition of AMI (rule-in/rule-out).
25 lis 2021 · Highly sensitive cardiac troponin T (hs-cTnT) has evolved into an essential diagnostic tool to detect myocardial injury—especially in patients presenting with acute chest pain. By definition, troponin T values above the 99th percentile compared to a healthy reference population are declared elevated [1, 2, 3].
1 lip 2022 · High-Sensitivity Cardiac Troponin and the 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guidelines for the Evaluation and Diagnosis of Acute Chest Pain. Circulation. 2022 Aug 16;146 (7):569-581. doi: 10.1161/CIRCULATIONAHA.122.059678. Epub 2022 Jul 1. Authors.
