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1 cze 2005 · A total of 521 serum samples was selected from cord blood, term and preterm neonates, infants and children up to the age of 15 years to establish reference intervals for high sensitive...
High CRP levels are known to be associated with early-onset neonatal sepsis (EOS), which is a serious and potentially life-threatening disease in newborns.
17 wrz 2018 · Multiple studies report higher mean/median CRP levels among infants delivered by VD and emergency cesarean delivery (CD) compared to elective CD.
CRP levels have been found to be helpful in differential diagnosis and in following the clinical course and response to treatment of various disorders. Of particular interest is their value in the diagnosis of serious bacterial infections in neonates, such as meningitis, septicemia, and osteomyelitis.
In recent years, much has been accomplished in clarifying its structure and its possible function in host immunity. This article summarizes current knowledge of CRP, with emphasis on clinical applications in pediatrics.
evidence suggests that CRP is an ex-cellent screen for serious bacterial in-fections in neonates. Because CRP does not cross the placenta, its pres-ence in a neonate indicates de novo production. Thus, some groups ad-vocate measurement of CRP in in-fants at risk for sepsis. These proto-cols recommend measuring CRP at
8 mar 2024 · CRP use in EOS evaluations varied widely across NICUs. High CRP use was associated with prolonged antibiotic therapy but not mortality ≤ 7 days after birth. Reducing routine CRP use in EOS evaluations may be a target for neonatal antibiotic stewardship efforts.
