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What does it mean if your Complement, Total (CH50) result is too high? Increased levels of complement may indicate: - Acute-phase immune response. - Cancer. - Ulcerative colitis. - Heart attack (acute myocardial infarction) - Sarcoidosis.
The reference ranges for total complement (total hemolytic complement: CH 50 [CH 100]), complement C3, and complement C4 are listed below.
High CH50 Levels. However, if your CH50 test shows high levels, it indicates an overactive complement system. This could signal an autoimmune disease where the body mistakenly attacks its cells. High levels might lead to symptoms like fatigue or joint pain but can vary widely among individuals.
9 sie 2022 · This topic review will discuss the functions of the complement system, the pathways involved, the measurement of complement activity, and the clinical significance of abnormally low or high complement tests.
Complement proteins may be measured individually or together. C3 and C4 proteins are the most commonly tested individual complement proteins. A CH50 test (sometimes called CH100) measures the amount and activity of all the major complement proteins.
30 mar 2010 · CH 50 is often decreased in SLE, glomerulonephritis and other immune complex diseases. A normal CH 50 level indicates that all the components, C1 through C9, are present. However, individual complement factors may be depleted 50 to 80% without affecting CH50 activity.
What does it mean if your Complement, Total (CH50) result is too high? Increased levels of complement may indicate: - Acute-phase immune response. - Cancer. - Ulcerative colitis. - Heart attack (acute myocardial infarction) - Sarcoidosis.
