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These European Association for the Study of the Liver recommendations on treatment of hepatitis C describe the optimal management of patients with recently acquired and chronic HCV infections in 2020 and onwards.
The goal of treatment in patients with chronic HCV infection is to attain a virologic cure, as evidenced by a sustained viral response, in order to reduce all-cause mortality and liver-related complications, including end-stage liver disease, hepatocellular carcinoma, and the morbidity and mortality associated with the extrahepatic manifestation...
5 kwi 2024 · (See "Clinical manifestations and natural history of chronic hepatitis C virus infection".) This topic addresses the general management of patients with chronic HCV infection. Patient selection for treatment and specific treatment regimens are discussed in detail elsewhere.
Summary. Interferon-free (IFN-free) treatment not only shortens treatment duration, but also achieves high rates of viral clearance and is overall well tolerated. Genotype-restricted but also pangenotypic combinations are available.
Adults with HCV infection who meet criteria for treatment with a simplified regimen should be treated with eight weeks of glecaprevir/pibrentasvir (Mavyret) or 12 weeks of...
Abstract. Hepatic encephalopathy (HE) is a common, severe complication of advanced chronic liver disease (CLD) and has a devastating impact on the patient’s quality of life and prognosis. The neurotoxin ammonia and the presence of systemic and neurological inflammation are considered the key drivers of this neuropsychiatric syndrome.
29 lip 2022 · Without treatment, chronic hepatitis C infection can cause liver complications, such as hepatic encephalopathy and even hepatic coma.
