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It should be considered when screening test results conflict (eg, antigen negative and microfilariae positive), when patients are receiving an alternative treatment protocol (eg, macrocyclic lactone and/or doxycycline), when the patient has known chronic inflammatory diseases (eg, pyoderma, otitis, endoparasitism), or when dogs test negative ...
9 lis 2017 · Research and development have been aimed at increasing sensitivity. Recently, heat treatment of serum prior to antigen testing has been shown to result in an increase in positive antigen test results, presumably due to disruption of natural antigen-antibody complexes.
The American Heartworm Society (AHS) recommends heartworm antigen testing to screen dogs without clinical signs and verify suspected heartworm infections. While patient-side antigen tests provide a vital tool for the practice, a full understanding of their role in heartworm diagnosis is essential.
A positive antigen test result should always be confirmed before treatment is pursued. The antigen-negative (NAD), microfilaria-positive dog presents several possibilities: Patient with only 1 or 2 female heartworms whose antigen levels are not detectable with patient-side test; Light infection, immature worms
26 kwi 2021 · The potential for HT leading to false-positive HW Ag tests by cross-reacting with other parasites has been evaluated in the field in naturally infected dogs.
9 sie 2022 · Ideally, microfilaria testing (modified Knott test, Millipore filter, direct smear, or microhematocrit technique) is performed along with antigen testing to confirm a positive antigen test result or help detect a false-negative result.
Heat treatment and false-positive heartworm antigen testing in ex vivo parasites and dogs naturally infected by Dirofilaria repens and Angiostrongylus vasorum Luigi Venco1*, Simone Manzocchi2, Marco Genchi3 and Laura H. Kramer3 From 15th American Heartworm Society Triennial Symposium New Orleans, LA, USA. September 11-13, 2016 Abstract
