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1. www.nature.com › articles › s41568/021/00358-wMitochondrial DNA variation and cancer - Nature Reviews Cancer

   www.nature.com › articles › s41568/021/00358-w

   27 maj 2021 · Variation in the mitochondrial DNA (mtDNA) sequence is common in certain tumours. Two classes of cancer mtDNA variants can be identified: de novo mutations that act as ‘inducers’ of...

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2. www.eupedia.com › europe › Haplogroup_T_mtDNAHaplogroup T (mtDNA) - Eupedia

   www.eupedia.com › europe › Haplogroup_T_mtDNA

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   Haplogroups T* (perhaps T1a) and T2b have been found in skeletons from late Mesolithic hunter-gatherers respectively from Russia and Sweden. It is the best evidence so far that haplogroup T was present in Europe before the continent was recolonised by Neolithic farmers.

3. en.wikipedia.org › wiki › Haplogroup_T_(mtDNA)Haplogroup T (mtDNA) - Wikipedia

   en.wikipedia.org › wiki › Haplogroup_T_(mtDNA)

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   Haplogroup T is a human mitochondrial DNA (mtDNA) haplogroup. It is believed to have originated around 25,100 years ago in the Near East. [citation needed] Mitochondrial clade T derives from the haplogroup JT, which also gave rise to the mtDNA haplogroup J. The T maternal clade is thought to have emanated from the Near East. [citation needed]

4. pmc.ncbi.nlm.nih.gov › articles › PMC8915179Functional Role of Mitochondrial DNA in Cancer Progression

   pmc.ncbi.nlm.nih.gov › articles › PMC8915179

   Functional and clinical studies have reported that mitochondrial DNA (mtDNA) mutations, mtDNA single-nucleotide polymorphisms (SNPs), mtDNA-encoded microRNAs (mitomiRs), mitochondria-derived long noncoding RNAs (lncRNAs) and mitochondrial proteins are involved in cancer progression (Figure 1).

5. pubmed.ncbi.nlm.nih.gov › 38826080Prospective of Mitochondrial DNA Variations in Cancer on Genomic...

   pubmed.ncbi.nlm.nih.gov › 38826080

   4 cze 2024 · Mitochondrial DNA (mtDNA) has emerged as a pivotal component in understanding the etiology and susceptibility of cancer. A recent study by Chen and colleagues delineated the germline genetic effect of mtDNA single-nucleotide polymorphisms (SNP) and haplogroups across pan-cancer risk.

6. bmcgenomdata.biomedcentral.com › articles › 10Mitochondria in tumour progression: a network of mtDNA variants...

   bmcgenomdata.biomedcentral.com › articles › 10

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   18 lut 2022 · Here, based on two independent datasets, we modelled an mtDNA mutation-cancer network by systematic integrative analysis including 37 cancer types to identify the mitochondrial variants found in common among them.

7. www.sciencedirect.com › science › articleMitochondrial inheritance and cancer - ScienceDirect

   www.sciencedirect.com › science › article

   1 gru 2018 · In this review, we summarize the current knowledge of mtDNA alterations, with a specific focus on somatic changes, germline variants, haplogroups, large deletions, and mtDNA content changes associated with cancer susceptibility and prognosis. We also discuss the potential of mtDNA as biomarkers of cancer detection and targets of cancer treatment.