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A hairpin is a special case of a turn, in which the direction of the protein backbone reverses and the flanking secondary structure elements interact. For example, the beta hairpin connects two hydrogen-bonded, antiparallel β-strands.
- Tertiary and Quaternary Structures
Table \(\PageIndex{1}\): pKa values of side chains in actual...
- Main Chain Conformations
The 310 helix, a sharper helix with 3 amino acids/turn,...
- Alpha Helix From Bacteriophage T4 Lysozyme (1Dyg)
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- PDB = 3Ua0
N-terminal part (domain) of the Bombyx mori fibroin silk...
- Pi Helix From beta-D-glucan Glucohydrolase (1X38)
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- TIM Barrel
No headers Interact with the model using Trackpad and Mouse...
- 1Dpx
Expand/collapse global hierarchy Home Learning Objects...
- 3-10Helix From Dienelactone Hydrolase (1Din)
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- Tertiary and Quaternary Structures
15 maj 2024 · A Stem-loop can be defined as a hairpin-like pattern formed because of the intramolecular base pairing of the nucleotide sequence (especially in palindromic sequence) within the same molecule. Here, the nucleotide pairs within the molecule to form a double helix structure ending in an unpaired loop resulting in a hairpin-like structure.
They are also referred to as hairpins or hairpin loops. A stem-loop occurs when two regions of the same nucleic acid strand, usually complementary in nucleotide sequence, base-pair to form a double helix that ends in a loop of unpaired nucleotides.
In their search of 54 proteins Miner-White, et. al. found 61 inverse γ-turns, but only one formed a β-hairpin producing a reversal in the peptide chain. [2] Example of an inverse gamma turn from proteinase A. Compare the structures of a classic and an inverse turns in the two applets below.
11 sie 2024 · Beta-hairpin or beta-turn This motif is present in most antiparallel beta structures, both as an isolated ribbon and as part of beta sheets. Figure \(\PageIndex{8}\) shows an interactive iCn3D model of the beta hairpin from bovine pancreatic trypsin inhibitor (1k6u)
Abstract. The structures of commonly occurring loop motifs and β -hairpins are described, with emphasis on their inter-main chain hydrogen bond patterns. Especially new is the realization that β -hairpins occur in four distinct classes that are of evolutionary and structural significance.
Hairpin DNA-functionalized gold nanoparticles (hAuNPs) for detection of mRNA in living cells. Hairpin DNA is coupled to the gold colloid surface via a 5′ hexane thiol, thereby quenching fluorescence emission of the 3′ fluorescent dye. The hairpin formation sequences maintain the hairpin conformation through complementary hydrogen bonding.