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The hairpin loop forms in an mRNA strand during transcription and causes the RNA polymerase to become dissociated from the DNA template strand. This process is known as rho-independent or intrinsic termination, and the sequences involved are called terminator sequences.
The hairpin loop forms in an mRNA strand during transcription and causes the RNA polymerase to become dissociated from the DNA template strand. This process is known as rho-independent or intrinsic termination, and the sequences involved are called terminator sequences.
Boulard Y, Gabarro-Arpa J, Cognet JAH, Le Bret M, Guy A, Teoule R, Guschlbauer W, Fazakerley GV (1991) The solution structure of a DNA hairpin containing a loop of three thymidines determined by nuclear magnetic resonance and molecular mechanics.
Hairpin DNA-functionalized gold nanoparticles (hAuNPs) for detection of mRNA in living cells. Hairpin DNA is coupled to the gold colloid surface via a 5′ hexane thiol, thereby quenching fluorescence emission of the 3′ fluorescent dye. The hairpin formation sequences maintain the hairpin conformation through complementary hydrogen bonding.
20 gru 2007 · Hairpin loops are critical to the formation of nucleic acid secondary structure, and to their function. Previous studies revealed a steep dependence of single-stranded DNA (ssDNA) hairpin stability with length of the loop ( L ) as ∼L 8.5 ± 0.5 , in 100 mM NaCl, which was attributed to intraloop stacking interactions.
10 paź 2021 · In our quest to establish whether the formation of parallel hairpin-G4s with long loops was feasible, we designed model hairpin-G4s with the sequence ‘TG 3 TG 3 TG 3 X (13/23/33) G 3 T’ in which the third loop (X) forms a hairpin.
