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In susceptible infected hosts, long-standing active chronic gastritis may result in gastric mucosal atrophy with intestinal metaplasia. In a minority, these premalignant mucosal changes progress to dysplasia and clinically silent, early cancer, followed by advanced gastric cancer.
19 sie 2023 · H. pylori infection is the most severe known risk factor for gastric cancer (GC), which is the second highest cause of cancer-related deaths globally. We conducted a systematic review and meta-analysis to assess the global prevalence of GC in H. pylori-infected individuals.
28 lip 2022 · Understanding the occurrence of H. pylori infection and its interaction with socio-demographic factors is important in developing an effective H. pylori infection risk management tools tailored to local public health policy.
10 paź 2023 · Eradication of H. pylori promotes healing of chronic non-atrophic gastritis and may lead to regression of atrophic gastritis and reduces the risk of gastric cancer in patients with non-atrophic and atrophic gastritis .
20 kwi 2023 · The risk of gastric cancer is highest in individuals who have infection by more virulent H. pylori strains, have pro-inflammatory host genetic factors, poor diet (high salt, smoked foods),...
29 sie 2022 · Helicobacter pylori (H. pylori) bacterial infection has long been scrutinized as one of the potential risk factors for the development of pancreatic cancer with quite inconsistent and...
29 maj 2024 · Helicobacter pylori treatment was associated with reduced gastric cancer risk for individuals with a high genetic risk during long-term follow-up but not for those with low genetic risk.