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12 kwi 2021 · Our report gives an early assessment of the B.1.1.7 variant's genomic characteristics and associated clinical outcomes, bridging the period over which B.1.1.7 became the predominant strain in two north-central London hospitals, mapping the start of the winter, 2020, surge in COVID-19 cases.
12 lis 2021 · Abstract. SARS-CoV-2 variants of concern (VOC) B.1.1.7 (alpha) and B.1.351 (beta) show increased transmissibility and enhanced antibody neutralization resistance. Here we demonstrate in...
28 cze 2024 · When these changes become significantly different to a previously detected virus, these new virus types are known as “variants.” To identify variants, scientists map the genetic material of viruses (known as sequencing) and then look for differences between them to see if they have changed.
14 lut 2022 · Thereby we identified a new B.1.1.7 sub-lineage carrying additional mutations of nucleoprotein G204P and open-reading-frame-8 K68stop. Of note, this B.1.1.7 sub-lineage is the predominant B.1.1.7 variant in several European countries such as Czech Republic, Austria, and Slovakia.
29 cze 2021 · SARS-CoV-2 variants with multiple amino acid mutations in the spike protein are emerging in different parts of the world, raising concerns regarding their possible impact on human immune response and vaccine efficacy against the virus. Recently, a variant named lineage B.1.1.7 was detected and shown ….
9 lis 2021 · To determine the structural basis for the enhanced infectivity mediated by the S protein of the dominant SARS-CoV-2 B.1.1.7 variant, we used cryo-electron microscopy (cryo-EM)...
6 lut 2021 · But three variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have raised particular concerns. On Jan 21, 2021, the UK New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG) issued a paper outlining the results from several preliminary analyses of B.1.1.7.
