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  1. Grape seed extract. Grape seed extract contains proanthocyanidin, which is a powerful antioxidant. Although, there are no studies on the topical use of grape seed extract, but oral intake for 6 months has been found beneficial in patients with melasma in a study conducted by Yamakoshi, et al.

  2. 21 lut 2024 · Hyperpigmentation of the skin, defined as increased melanin in the epidermis, is a common condition associated with psychosocial impairment and decreased quality of life. Prescription options are often not covered by insurance and can be cost prohibitive. As such, many turn to over-the-counter (OTC) products for treatment.

  3. Oral intake of grape seed extracts (67 mg of grape seed extract) 3 times daily for 6 months was reported to be effective in reducing hyperpigmentation in patients with melasma. 73 Although these agents produced promising results, additional studies regarding the treatment of PIH are needed.

  4. Chloasma (melasma), an acquired hypermelanosis, is often recalcitrant to various treatments and an amenable, as well as safe, pigment-reducing modality is needed. We investigated that the reducing effect of proanthocyanidin, a powerful antioxidant, on chloasma in a one-year open design study.

  5. 26 lip 2024 · Explore the potential of grapefruit seed extract and grape seed extract in treating melasma. Learn how they work, scientific studies, benefits, drawbacks, and alternatives. Plus, precautions and recommendations for use.

  6. Yamakoshi et al. demonstrated the skin-lightening property of proanthocyanidin-rich grape seed extract in the treatment of melasma on Japanese women. Thus, most of these agents are used as over-the-counter adjuncts without much credible scientific evidence.

  7. 16 lip 2024 · This article delves into the antioxidant properties of grape seed extract, its effects on skin health, and scientific studies that link it to melasma improvement. Learn how it may help, weigh the benefits and risks, and discover alternative treatments for this common skin condition.

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