Search results
Grape seed extract. Grape seed extract contains proanthocyanidin, which is a powerful antioxidant. Although, there are no studies on the topical use of grape seed extract, but oral intake for 6 months has been found beneficial in patients with melasma in a study conducted by Yamakoshi, et al.
Melanin-index significantly decreased after 6 months of the intake (0.025 +/- 0.005 at the start vs 0.019 +/- 0.004 at 6 months) (p < 0.01), and also decreased at the end of study (0.021 +/- 0.005) (p < 0.05). GSE is effective in reducing the hyperpigmentation of women with chloasma.
21 lut 2024 · Hyperpigmentation of the skin, defined as increased melanin in the epidermis, is a common condition associated with psychosocial impairment and decreased quality of life. Prescription options are often not covered by insurance and can be cost prohibitive. As such, many turn to over-the-counter (OTC) products for treatment.
26 lip 2024 · Explore the potential of grapefruit seed extract and grape seed extract in treating melasma. Learn how they work, scientific studies, benefits, drawbacks, and alternatives. Plus, precautions and recommendations for use.
7 cze 2017 · Oral grape seed extract can reduce the appearance of melasma by inhibiting melanin synthesis and UV-induced hyperpigmentation .
Yamakoshi et al. demonstrated the skin-lightening property of proanthocyanidin-rich grape seed extract in the treatment of melasma on Japanese women. Thus, most of these agents are used as over-the-counter adjuncts without much credible scientific evidence.
1 lis 2004 · Proanthocyanidin‐rich grape seed extract (GSE) was orally administered to 12 Japanese woman candidates with chloasma for 6 months between August 2001 and January 2002 and to 11 of these 12 for 5 months between March and July 2002.
