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  1. Melanin-index significantly decreased after 6 months of the intake (0.025 +/- 0.005 at the start vs 0.019 +/- 0.004 at 6 months) (p < 0.01), and also decreased at the end of study (0.021 +/- 0.005) (p < 0.05). GSE is effective in reducing the hyperpigmentation of women with chloasma.

  2. 9 sie 2024 · From understanding its properties to scientific evidence, benefits, application methods, and precautions, this article covers everything you need to know about using grape seed extract for melasma. Discover alternative treatments and get expert recommendations for effective melasma management.

  3. Grape seed extract. Grape seed extract contains proanthocyanidin, which is a powerful antioxidant. Although, there are no studies on the topical use of grape seed extract, but oral intake for 6 months has been found beneficial in patients with melasma in a study conducted by Yamakoshi, et al.

  4. 26 lip 2024 · Explore the potential of grapefruit seed extract and grape seed extract in treating melasma. Learn how they work, scientific studies, benefits, drawbacks, and alternatives. Plus, precautions and recommendations for use.

  5. 16 lip 2024 · This article delves into the antioxidant properties of grape seed extract, its effects on skin health, and scientific studies that link it to melasma improvement. Learn how it may help, weigh the benefits and risks, and discover alternative treatments for this common skin condition.

  6. 23 mar 2021 · Jun Y, Atsushi S, Shoichi T, et al. Oral intake of proanthocyanidin-rich extract from grape seeds improves chloasma. Phytother Res. 2004; 18:895–899. doi: 10.1002/ptr.1537 [Google Scholar]

  7. 21 maj 2019 · The grape seed extract (GSE) and its main active polyphenol, resveratrol (RES), have shown considerable antioxidant activities, besides possessed protective and therapeutic effects against various skin complications.

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