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Certain inflammatory diseases are characterised by a combination of granulomatous inflammation and vasculitis (inflammation of the blood vessels). Both the granulomas as well as the vasculitis tend to occur in association with necrosis.
- Chronic granulomatous disease
Chronic granulomatous disease is the name for a genetically...
- Chronic granulomatous disease
Przewlekła choroba ziarniniakowa (CGD, z ang. chronic granulomatous disease) – pierwotny niedobór odporności, którego przyczyną są występujące w fagocytach zaburzenia przetwarzania tlenu w jego reaktywne formy [1] [2] [3].
Chronic granulomatous disease is the name for a genetically heterogeneous group of immunodeficiencies. The core defect is a failure of phagocytic cells to kill organisms that they have engulfed because of defects in a system of enzymes that produce free radicals and other toxic small molecules.
Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatosis (WG), [1] [2] [3] [4] [5] after the German physician Friedrich Wegener, is a rare long-term systemic disorder that involves the formation of granulomas and inflammation of blood vessels (vasculitis).
Introduction. Granulomatous inflammation is a unique form of chronic inflammation.1 Granulomas are distinct structures composed of epithelioid-shaped macrophages, multinucleated giant cells, lymphocytes, and fibroblasts. However, the clinical findings associated with granulomatous inflammation are usually variable and often indistinct.
A granuloma, also granulomatous inflammation, is a distinctive histomorphologic finding. Granulomas can be elusive to the novice. The plural of granuloma was granulomata; granulomas (an anglicized version) is, however, now generally accepted.
19 wrz 2022 · A granuloma is a focal aggregate of immune cells that forms in response to a persistent inflammatory stimulus. It characteristically demonstrates the compact organization of mature macrophages, which may or may not be associated with other inflammatory cell types.
