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4 paź 2019 · The rough endoplasmic reticulum plays an important role in synthesizing proteins destined for secretion from the cell. Therefore, it is studded with ribosomes and polysomes, which are translating mRNA containing the code for these proteins.
Rough endoplasmic reticulum (ER) sheets are a fundamental domain of the ER and the gateway into the secretory pathway. Although reticulon proteins stabilize high-curvature ER tubules, it is unclear whether other proteins scaffold the flat membranes of rough ER sheets.
The endoplasmic reticulum (ER), typically the largest membrane-bound organelle in a eukaryotic cell, plays a critical role in many cellular processes, including protein synthesis, protein modification, lipid synthesis and the regulation of Ca 2+ homeostasis and secretion [1].
Protein translocation across the rough endoplasmic reticulum (RER) is an ancient and evolutionarily conserved process that is analogous to protein export across the cytoplasmic membranes of eubacterial and archaebacterial cells both with respect to the mechanism and core components.
27 kwi 2015 · The endoplasmic reticulum (ER) supports many cellular processes and performs diverse functions, including protein synthesis, translocation across the membrane, integration into the membrane, folding, and posttranslational modifications including N-linked glycosylation; and regulation of Ca2+ homeostasis.
Whereas some quiescent cell types secrete minor amounts of proteins, tissues like the pancreas, producing insulin and other hormones, and mature B cells, producing antibodies, place a great demand on their endoplasmic reticulum (ER).
5 paź 2015 · The endoplasmic reticulum (ER) is a large, dynamic structure that serves many roles in the cell including calcium storage, protein synthesis and lipid metabolism. The diverse functions of the ER are performed by distinct domains; consisting of tubules, sheets and the nuclear envelope.
